The Four Sons of Horus were traditionally the guardians of the internal organs of the deceased. Each was associated with a particular organ, and also with a different cardinal point on the compass.
| God | Protects | Head | Point | Goddess |
| Imsety | Liver | Human | South | Isis |
| Hapy | Lungs | Baboon | North | Nephthys |
| Duamutef | Stomach | Jackal | East | Neit |
| Qebehsenuef | Intestines | Falcon | West | Selkis |
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Canopic jars for "King Tut" |